Researchers discovered that common, low-intensity use of antibiotics might play more of a part in the antibiotic resistance than high-intensity, frequent use by a small fraction of the population. The rising occurrence of antibiotic resistance in the U.S. seems more closely associated with their rare use by numerous individuals than by their frequent use amongst lesser numbers of individuals, according to the novel study carried out at the Harvard T.H. Chan School of Public Health.
The research also discovered that antibiotic use differs across the nation. It also highlighted that, in areas where specific antibiotics are used more often, resistance to those types of antibiotics is higher. Yonatan Grad, Melvin J. and Geraldine L. Glimcher Assistant Professor, Immunology and Infectious Diseases, is the senior author of this research. He proclaimed that the research team was aware that efforts to minimize inapt use of antibiotics are critical for addressing the issue of antibiotic resistance.
On a similar note, recently, a research was carried out on the poison of insects, such as bees and wasps. This poison contains compounds that can destroy bacteria. Unfortunately, numerous of these compounds are also poisonous for humans as well. This makes it impossible to employ them as antibiotic medicines. After carrying out systematic research on the antimicrobial qualities of a toxin generally found in a South American wasp, scientists from MIT have now formed alternatives of the peptide that are effective against bacteria and, at the same time, harmless to human cells.
In a research carried out on mice, the scientists discovered that their most powerful peptide might totally remove Pseudomonas aeruginosa, a strain of bacteria that forms respiratory and other infections. It is resistant to the majority of antibiotics. Cesar de la Fuente-Nunez, Postdoctoral Associate & Areces Foundation Junior Fellow, MIT, stated that the research team has repurposed a poisonous molecule into one that is practicable to treat numerous infections.